Entity Central Index Key Amount of lessee's undiscounted obligation for lease payment for operating lease due after fourth fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach). Cover [Abstract] Document Type Document Type Amendment Flag Amendment Flag Document Period End Date Document Period End Date Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal Period Focus Trading Symbol Trading Symbol Entity Registrant Name Entity Registrant Name Entity Central Index Key Current Fiscal Year End Date Current Fiscal Year End Date Entity Filer Category Entity Filer Category Entity Small Business Entity Small Business Entity Emerging Growth Company Entity Emerging Growth Company Entity Common Stock, Shares Outstanding Entity Common Stock Shares Outstanding Entity Current Reporting Status Entity Current Reporting Status Entity Shell Company Entity Shell Company Entity File Number Entity File Number Entity Tax Identification Number Entity Tax Identification Number Entity Address, Address Line One Entity Address Address Line1 Entity Address, Address Line Two Entity Address Address Line2 Entity Address, City or Town Entity Address City Or Town Entity Address, State or Province Entity Address State Or Province Entity Address, Postal Zip Code Entity Address Postal Zip Code City Area Code City Area Code Local Phone Number Local Phone Number Title of 12(b) Security Security12b Title Security Exchange Name Security Exchange Name Entity Interactive Data Current Entity Interactive Data Current Document Quarterly Report Document Quarterly Report Document Transition Report Document Transition Report Entity Incorporation State Country Code Entity Incorporation State Country Code Statement Of Financial Position [Abstract] Assets Assets [Abstract] Current assets: Assets Current [Abstract] Cash and cash equivalents Cash And Cash Equivalents At Carrying Value Marketable debt securities Available For Sale Securities Debt Securities Current Prepaid expenses and other current assets Prepaid Expense And Other Assets Current Total current assets Assets Current Property and equipment, net Property Plant And Equipment Net Operating lease right-of-use assets Operating Lease Right Of Use Asset Restricted cash Restricted Cash Noncurrent Other assets Other Assets Noncurrent Total assets Assets Liabilities and Stockholders’ Equity Liabilities And Stockholders Equity [Abstract] Current liabilities: Liabilities Current [Abstract] Accounts payable Accounts Payable Current Accrued expenses Accrued Liabilities Current Operating lease liabilities, current Operating Lease Liability Current Total current liabilities Liabilities Current Operating lease liabilities Operating Lease Liability Noncurrent Total liabilities Liabilities Commitments and contingencies (See Note 9) Commitments And Contingencies Stockholders’ equity: Stockholders Equity [Abstract] Preferred stock; $0.001 par value per share; 5,000,000 shares authorized as of March 31, 2021 and December 31, 2020; no shares issued and outstanding as of March 31, 2021 and December 31, 2020 Preferred Stock Value Common stock, $0.001 par value per share; 115,000,000 shares authorized as of March 31, 2021 and December 31, 2020; 15,367,730 shares issued and outstanding as of March 31, 2021 and December 31, 2020, respectively Common Stock Value Additional paid-in capital Additional Paid In Capital Common Stock Accumulated deficit Retained Earnings Accumulated Deficit Accumulated other comprehensive loss Accumulated Other Comprehensive Income Loss Net Of Tax Total stockholders’ equity Stockholders Equity Total liabilities and stockholders’ equity Liabilities And Stockholders Equity Preferred stock, par value per share Preferred Stock Par Or Stated Value Per Share Preferred stock, shares authorized Preferred Stock Shares Authorized Preferred stock, shares issued Preferred Stock Shares Issued Preferred stock, shares outstanding Preferred Stock Shares Outstanding Common stock, par value per share Common Stock Par Or Stated Value Per Share Common stock, shares authorized Common Stock Shares Authorized Common stock, shares issued Common Stock Shares Issued Common stock, shares outstanding Common Stock Shares Outstanding Income Statement [Abstract] Operating expenses: Operating Expenses [Abstract] Research and development Research And Development Expense General and administrative General And Administrative Expense Total operating expenses Operating Expenses Loss from operations Operating Income Loss Other income, net Nonoperating Income Expense Net loss Net Income Loss Net loss per share, basic and diluted Earnings Per Share Basic And Diluted Weighted average common shares outstanding, basic and diluted Weighted Average Number Of Share Outstanding Basic And Diluted Comprehensive loss: Comprehensive Income Net Of Tax [Abstract] Net loss Other comprehensive loss: Other Comprehensive Income Loss Net Of Tax Portion Attributable To Parent [Abstract] Unrealized gain (loss) on marketable debt securities Other Comprehensive Income Availableforsale Securities Adjustment Net Of Tax Portion Attributable To Parent Total other comprehensive loss Other Comprehensive Income Loss Net Of Tax Portion Attributable To Parent Total comprehensive loss Comprehensive Income Net Of Tax Statement Of Stockholders Equity [Abstract] Statement [Table] Statement [Table] Equity Components Statement Equity Components [Axis] Equity Component Equity Component [Domain] Common Stock [Member] Common Stock [Member] Additional Paid-in Capital [Member] Additional Paid In Capital [Member] Accumulated Deficit [Member] Retained Earnings [Member] Accumulated Other Comprehensive Loss [Member] Accumulated Other Comprehensive Income [Member] Statement [Line Items] Statement [Line Items] Beginning balance Beginning balance, shares Shares Outstanding Capital contributions from related party Proceeds From Contributed Capital Stock-based compensation expense Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value Ending balance Ending balance, shares The increase (decrease) in the right-of-use assets during the reporting period. The increase (decrease) in operating lease liabilities during the reporting period. The cash outflow associated with merger transaction costs. Future cash outflow to pay for offering costs that have occurred related to an offering of securities. Future cash outflow to pay for transaction costs that have occurred related to a merger. Future cash outflow to pay for leasehold improvements on right-of-use assets. Statement Of Cash Flows [Abstract] Cash flows from operating activities: Net Cash Provided By Used In Operating Activities [Abstract] Net loss Profit Loss Adjustments to reconcile net loss to net cash used in operating activities: Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract] Stock-based compensation expense Share Based Compensation Depreciation expense Depreciation Amortization of premium on marketable securities Investment Income Net Amortization Of Discount And Premium Changes in operating assets and liabilities: Increase Decrease In Operating Capital [Abstract] Prepaid expenses and other current assets Increase Decrease In Prepaid Deferred Expense And Other Assets Accounts payable Increase Decrease In Accounts Payable Accrued expenses Increase Decrease In Accrued Liabilities Right-of-use assets Increase Decrease In Right Of Use Assets Operating lease liabilities Increase Decrease In Operating Lease Liabilities Other assets Increase Decrease In Other Noncurrent Assets Net cash used in operating activities: Net Cash Provided By Used In Operating Activities Cash flows from investing activities: Net Cash Provided By Used In Investing Activities [Abstract] Purchase of property and equipment Payments To Acquire Property Plant And Equipment Purchase of marketable securities Payments To Acquire Available For Sale Securities Debt Maturities and sales of marketable securities Proceeds From Sale And Maturity Of Available For Sale Securities Merger transaction costs Payments Of Merger Transaction Costs Net cash provided by (used in) investing activities Net Cash Provided By Used In Investing Activities Cash flows from financing activities: Net Cash Provided By Used In Financing Activities [Abstract] Offering costs Payments Of Stock Issuance Costs Net cash provided by financing activities Net Cash Provided By Used In Financing Activities Net increase in cash, cash equivalents and restricted cash Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect Cash, cash equivalents and restricted cash at beginning of period Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations Cash, cash equivalents and restricted cash at end of period Supplemental disclosure of non-cash investing and financing activities: Cash Flow Noncash Investing And Financing Activities Disclosure [Abstract] Property and equipment included in accounts payable and accrued expenses Capital Expenditures Incurred But Not Yet Paid Offering costs included in accounts payable and accrued expense Offering Costs Incurred But Not Yet Paid Merger transaction costs included in accounts payable and accrued expenses Merger Transaction Costs Incurred But Not Yet Paid Leased assets obtained in exchange for new operating lease liabilities Right Of Use Asset Obtained In Exchange For Operating Lease Liability Payment of leasehold improvements on right-of-use assets included in operating lease liability, current Leasehold Improvements On Right Of Use Assets Included In Operating Lease Liability Current Organization Consolidation And Presentation Of Financial Statements [Abstract] Organization, Nature of the Business, COVID-19 Risk and Basis of Presentation Business Description And Basis Of Presentation [Text Block] Accounting Policies [Abstract] Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Business Combinations [Abstract] Merger Accounting Mergers Acquisitions And Dispositions Disclosures [Text Block] Fair Value Disclosures [Abstract] Fair Value Measurements and Marketable Debt Securities Fair Value Disclosures [Text Block] The entire disclosure for prepaid expenses and other current assets. Prepaid Expense And Other Assets [Abstract] Prepaid Expenses and Other Current Assets Prepaid Expenses And Other Current Assets [Text Block] Fixed Assets Property Plant And Equipment Disclosure [Text Block] Payables And Accruals [Abstract] Accrued Expenses Accounts Payable Accrued Liabilities And Other Liabilities Disclosure Current [Text Block] Stockholders Equity Note [Abstract] Stockholders' Equity and Stock Options Stockholders Equity Note Disclosure [Text Block] Commitments And Contingencies Disclosure [Abstract] Commitments Commitments And Contingencies Disclosure [Text Block] Related Party Transactions [Abstract] Related Party Transactions Related Party Transactions Disclosure [Text Block] Merger with Zafgen Business Combinations Policy Basis of Presentation Basis Of Accounting Policy Policy [Text Block] Disclosure of accounting policy for a reverse stock split. Reverse Stock Split Reverse Stock Split Policy [Text Block] Disclosure of accounting policy for the assessment of the ability to continue as a going concern. Going Concern Assessment Going Concern Policy [Text Block] Use of Estimates Use Of Estimates Concentrations of Credit Risk and Significant Suppliers Concentration Risk Credit Risk Cash and Cash Equivalents Cash And Cash Equivalents Policy [Text Block] Marketable Debt Securities Marketable Securities Policy Property and Equipment Property Plant And Equipment Policy [Text Block] Impairment of Long-Lived Assets Impairment Or Disposal Of Long Lived Assets Policy [Text Block] Segment Information Segment Reporting Policy Policy [Text Block] Research and Development Costs Research And Development Expense Policy Patent Costs Intangible Assets Finite Lived Policy Stock-Based Compensation Share Based Compensation Option And Incentive Plans Policy Income Taxes Income Tax Policy [Text Block] Net Loss Per Share Earnings Per Share Policy [Text Block] Recently Issued and Adopted Accounting Pronouncements New Accounting Pronouncements Policy Policy [Text Block] Tabular disclosure of the preliminary estimate of the purchase price paid as part of a merger. May include, but is not limited to, information for shares issued (number, fair value per share, total fair value) and transaction costs. Summary of Purchase Price Paid in Merger Summary Of Estimated Purchase Price Paid In Merger Table [Text Block] Summary of Allocation of Purchase Price to Net Tangible and Intangible Assets Acquired Schedule Of Recognized Identified Assets Acquired And Liabilities Assumed Table [Text Block] Summary of Cash Equivalents and Marketable Debt Securities Fair Value Assets Measured On Recurring And Nonrecurring Basis Table [Text Block] Summary of Marketable Debt Securities Schedule Of Available For Sale Securities Reconciliation Table [Text Block] Tabular disclosure of the carrying amounts of prepaid expenses and other current assets. Schedule of Prepaid Expenses and Other Current Assets Schedule Of Prepaid Expenses And Other Current Assets Table [Text Block] Schedule of Fixed Assets, Net Property Plant And Equipment [Text Block] Schedule of Accrued Expenses Schedule Of Accrued Liabilities Table [Text Block] Assumptions used to Determine Fair Value of Stock Options Granted Schedule Of Share Based Payment Award Stock Options Valuation Assumptions Table [Text Block] Summary of Stock Option Activity Schedule Of Share Based Compensation Stock Options Activity Table [Text Block] Summary of Stock-Based Compensation Expense Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Text Block] Schedule of Maturities of Lease Liabilities Due Under Lease Agreements Lessee Operating Lease Liability Maturity Table [Text Block] If determined, state the month and year in which SAD Phase 1 clinical trial resumed & conducting the clinical trial at one clinical trial site. Consolidated Entities Consolidated Entities [Axis] Consolidated Entities Consolidated Entities [Domain] Zafgen. Zafgen [Member] Zafgen [Member] Chondrial. Chondrial [Member] Chondrial [Member] Business Acquisition Business Acquisition [Axis] Business Acquisition, Acquiree Business Acquisition Acquiree [Domain] The number of common stock shares issued in exchange for one share of the other company's common stock as part of a merger agreement. Merger Agreement [Member] Merger Agreement [Member] Sale of Stock Subsidiary Sale Of Stock [Axis] Sale of Stock Sale Of Stock Name Of Transaction [Domain] Private offering of securities, as part of a merger agreement. Private Offering [Member] Private Offering [Member] At the market offering member. ATM Offering [Member] At The Market Offering [Member] Statistical Measurement Range [Axis] Statistical Measurement Range [Member] Maximum [Member] Maximum [Member] Minimum [Member] Minimum [Member] Phase 1 clinical trial resume period Phase1 Clinical Trial Resume Period The number of common stock shares issued in exchange for one share of the other company's common stock as part of a merger agreement. Reverse stock split of common stock Stockholders Equity Reverse Stock Split Exchange rate of shares issued per share Exchange Rate Of Shares Issued Per Share Amount of cash, cash equivalents and marketable securities. Net loss Cash, cash equivalents and marketable securities Cash Cash Equivalents Marketable Securities The acquisition of cash, cash equivalents, restricted cash and marketable debt securities that was held by the acquired company, as part of a merger agreement. Proceeds from issuance of common stock and prefunded warrants to purchase common stock, net of offering costs. The potential aggregate gross sales proceeds available under a sales agreement to sell shares of the Company's common stock. Cash, cash equivalents, restricted cash and marketable debt securities acquired merger Cash Cash Equivalents Restricted Cash And Marketable Debt Securities Acquired Merger Proceeds from issuance common stock and warrants net offering costs Proceeds From Issuance Common Stock And Warrants Net Offering Costs Capital contributions from related party Aggregate sale of shares of our common stock Aggregate Gross Sales Proceeds Under Sales Agreement Issuance of common stock Stock Issued During Period Shares New Issues Proceeds from issuance of common stock Proceeds From Issuance Of Common Stock Sale of stock, price per share Sale Of Stock Price Per Share The minimum likelihood percentage threshold used to determine the amount of tax benefit to be recognized. Summary of significant accounting policies. Summary of significant accounting policies. Summary Of Significant Accounting Policies [Table] Summary Of Significant Accounting Policies [Table] Antidilutive Securities Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis] Antidilutive Securities, Name Antidilutive Securities Name [Domain] Common Stock Equivalents. Common Stock Equivalents [Member] Common Stock Equivalents [Member] Summary Of Significant Accounting Policies [Line Items] Summary Of Significant Accounting Policies [Line Items] Percentage of likelihood to be realized upon ultimate settlement, description Likelihood Percentage Minimum Warrant issued Class Of Warrant Or Right Number Of Securities Called By Warrants Or Rights Warrant Excercise Price Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1 Total potentially dilutive shares Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount Schedule Of Business Acquisitions By Acquisition [Table] Schedule Of Business Acquisitions By Acquisition [Table] Equity Interest Type Equity Interest Issued Or Issuable By Type [Axis] Equity Interest Issued or Issuable, Type Equity Interest Issued Or Issuable Type [Domain] Chondrial therapeutics inc. Chondrial Therapeutics Inc. [Member] Chondrial Therapeutics Inc [Member] Option Indexed to Issuer's Equity, Type Option Indexed To Issuers Equity Type [Axis] Option Indexed to Issuer's Equity, Type Option Indexed To Issuers Equity Type [Domain] Options to Purchase Common Stock [Member] Employee Stock Option [Member] Business Acquisition [Line Items] Business Acquisition [Line Items] Capital stock ownership percentage Equity Method Investment Ownership Percentage Common stock, shares issued Options to purchase stock Stock Issued During Period Shares Acquisitions Number of shares of the combined organization owned by Zafgen stockholders Stockholders Equity Note Changes In Capital Structure Subsequent Changes To Number Of Common Shares Multiplied by the fair value per share of Zafgen common stock Business Acquisition Share Price Fair value of consideration issued in effect of the Merger Business Combination Consideration Transferred1 Transaction costs Business Acquisition Cost Of Acquired Entity Transaction Costs Purchase price: Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Net Common stock outstanding Amount of other assets expected to be realized or consumed both before one year or the normal operating cycle, if longer, and after one year or the normal operating cycle, if longer, acquired at the acquisition date. Amount of cash restricted as to withdrawal or usage, acquired at the acquisition date. Amount of lessee's right to use underlying asset under operating lease, acquired at the acquisition date. Amount of lease liabilities due after one year or the normal operating cycle, if longer, assumed at the acquisition date. Cash and cash equivalents Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Cash And Equivalents Marketable debt securities Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Current Assets Marketable Securities Other current and noncurrent assets Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Other Current And Noncurrent Assets Property and equipment, net Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Property Plant And Equipment Restricted cash Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Restricted Cash Right-of-use asset Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Right Of Use Asset Current liabilities Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Current Liabilities Lease liability, net of current portion Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Capital Lease Obligation Noncurrent Purchase price Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Fair Value Hierarchy and NAV Fair Value By Fair Value Hierarchy Level [Axis] Fair Value Hierarchy and NAV Fair Value Measurements Fair Value Hierarchy [Domain] Quoted Prices in Active Markets, (Level 1) [Member] Fair Value Inputs Level1 [Member] Significant Other Observable Inputs (Level 2) [Member] Fair Value Inputs Level2 [Member] Significant Unobservable Inputs (Level 3) [Member] Fair Value Inputs Level3 [Member] Investment Type Investment Type [Axis] Investments Investment Type Categorization [Member] Money Market Funds [Member] Money Market Funds [Member] Commercial Paper [Member] Commercial Paper [Member] Corporate Bonds [Member] Corporate Bond Securities [Member] U.S. Government Securities [Member] U S Government Corporations And Agencies Securities [Member] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Cash equivalents Cash And Cash Equivalents Fair Value Disclosure Total cash equivalents and marketable debt securities Assets Fair Value Disclosure Debt Securities Available For Sale [Table] Debt Securities Available For Sale [Table] Schedule Of Available For Sale Securities [Line Items] Schedule Of Available For Sale Securities [Line Items] Amortized Cost Available For Sale Debt Securities Amortized Cost Basis Gross Unrealized Gains Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax Gross Unrealized Losses Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax Fair Value Allowance for credit losses Debt Securities Available For Sale Allowance For Credit Loss Amount of asset related to consideration paid in advance for costs related to research and development. Carrying amount as of the balance sheet date of payroll taxes previously overpaid to tax authorities (such as U.S. Federal, state and local tax authorities) representing refunds of overpayments or recoveries based on agreed-upon resolutions of disputes. Amount of asset related to consideration paid in advance for costs that provide economic benefits in future periods, and amount of other assets that are expected to be realized or consumed within one year or the normal operating cycle, if longer, not separately disclosed. Prepaid research and development expenses Prepaid Research And Development Expenses Prepaid insurance Prepaid Insurance Payroll tax receivable Payroll Taxes Receivable Other prepaid expenses and other assets Other Prepaid Expense And Other Current Assets Total prepaid expenses and other current assets Long-Lived Tangible Asset Property Plant And Equipment By Type [Axis] Long-Lived Tangible Asset Property Plant And Equipment Type [Domain] Computer Equipment [Member] Computer Equipment [Member] Lab Equipment [Member] Equipment [Member] Furniture and Fixtures [Member] Furniture And Fixtures [Member] Lease hold Improvements [Member] Leasehold Improvements [Member] Fixed assets, gross Property Plant And Equipment Gross Less: Accumulated depreciation Accumulated Depreciation Depletion And Amortization Property Plant And Equipment Fixed assets, net Fixed assets, useful life Property Plant And Equipment Useful Life Fixed assets, useful life Property Plant And Equipment Estimated Useful Lives Carrying value as of the balance sheet date of obligations incurred through that date and payable for expenses related to research and development. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Accrued research and development expenses Accrued Research And Development Expense Current Accrued payroll and related expenses Employee Related Liabilities Current Accrued professional fees Accrued Professional Fees Current Accrued other Other Accrued Liabilities Current Total accrued expenses Private Placement [Member] Private Placement [Member] Related Party Transaction Related Party Transaction [Axis] Related Party Transaction Related Party Transaction [Domain] MTS Health Partners. MTS Health Partners [Member] M T S Health Partners [Member] At-the-market equity offering program. ATM Offering Program [Member] At The Market Equity Offering Program [Member] Plan Name Plan Name [Axis] Plan Name Plan Name [Domain] Two thousand twenty equity incentive plan. 2020 Equity Incentive Plan [Member] Two Thousand Twenty Equity Incentive Plan [Member] Two thousand fourteen stock option and incentive plan. 2014 Stock Option and Incentive Plan [Member] Two Thousand Fourteen Stock Option And Incentive Plan [Member] Two thousand sixteen equity and incentive plan. 2016 Equity and Incentive Plan [Member] Two Thousand Sixteen Equity And Incentive Plan [Member] Nature of Expense Nature Of Expense [Axis] Interim Period, Costs Not Allocable Interim Period Costs Not Allocable [Domain] Vested recognized immediately. Vested Recognized Immediately [Member] Vested Recognized Immediately [Member] Nonvested recognize over remaining term. Nonvested Recognize Over Remaining Term [Member] Nonvested Recognize Over Remaining Term [Member] Vesting Vesting [Axis] Vesting Vesting [Domain] First anniversary. First Anniversary [Member] First Anniversary [Member] Preferred stock, par value Common stock, par value Common stock voting rights Common Stock Voting Rights Dividend paid Dividends Payable Current And Noncurrent Per unit amount of prefunded warrant issued. Costs incurred during the period related to the issuance of stock and warrants. Share price per share Shares Issued Price Per Share Warrants price per share Warrants Issued Price Per Share Gross proceeds Proceeds From Issuance Of Private Placement Transaction cost Stock And Warrant Issuance Transaction Costs Issuance of common stock as compensation to placement agency Stock Issued During Period Shares Issued For Services Aggregate sale of shares of our common stock The fee for services as a percentage of gross proceeds resulting from the sale of shares of common stock under a sales agreement. Description of sales agreement.. Percentage of compensation for services equal to gross proceeds Percentage Of Compensation For Services Equal To Gross Proceeds Sales agreement, description Sales Agreement Description Net proceeds from issuance of common stock Average price per share The minimum threshold number of shares used to determine the maximum number of shares that may be issued under the Plan. The maximum aggregate number of shares that may be issued under a share-based payment arrangement over the full term of the plan. The maximum number of shares that may be added annually to the threshold number of shares issued under the Plan, as a percentage of the shares issued and outstanding on the last day of the immediately preceding fiscal year. The term of the plan. Share-based compensation arrangement by share-based payment award, description Share Based Compensation Arrangement By Share Based Payment Award Terms Of Award Shares available for grant Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Minimum level of maximum number of shares allowed to be issued Share Based Compensation Arrangement By Share Based Payment Award Threshold Number Of Shares Allowed To Issue Increase in shares reserved for future issuance Share Based Compensation Arrangement By Share Based Payment Award Number Of Additional Shares Authorized Maximum number of shares that may be issued under stock option incentive plan Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Authorized Maximum aggregate shares issuable over plan term Share Based Compensation Arrangement By Share Based Payment Award Maximum Aggregate Number Of Shares Issuable Over Plan Term Percentage of outstanding shares Share Based Compensation Arrangement By Share Based Payment Award Additional Shares Percentage Of Outstanding Stock Term of the 2020 plan Share Based Compensation Arrangement By Share Based Payment Award Duration Shares reserved for future issuance Common Stock Capital Shares Reserved For Future Issuance The increase or decrease in number of shares reserved for issuance under stock option agreements awarded under the plan that validly exist and are outstanding, including vested options. Issuance of options Issuance Of Options The number of outstanding and unexercised options to purchase common units available immediately prior to a merger. The number of outstanding and unexercised options to purchase common units available immediately after a merger. The weighted average exercise price of outstanding and unexercised options to purchase common units available immediately after a merger. The weighted average exercise price of outstanding and unexercised options to purchase common units available immediately prior to a merger. Number of options to purchase common unit prior to conversion Number Of Options To Purchase Common Unit Prior To Conversion Number of options to purchase common unit post conversion Number Of Options To Purchase Common Unit Post Conversion Weighted average exercise price post conversion Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price Post Conversion Weighted average exercise price prior to conversion Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price Prior To Conversion The aggregate grant-date fair value of stock options or units. Increase in fair value Increase Decrease In Fair Value Of Price Risk Fair Value Hedging Instruments1 Aggregate grant fair value Share Based Compensation Arrangement By Share Based Payment Award Aggregate Grant Date Fair Value1 Risk-free interest rate Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Expected term (in years) Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1 Expected volatility Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Dividend yield Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate Number of shares, Outstanding Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number Number of shares, Granted Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross Number of shares, Forfeited Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period Number of shares, Outstanding Number of shares, Exercisable as of March 31, 2021 Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number Number of shares, Vested and expected to vest as of March 31, 2021 Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Number Weighted average exercise price, balance Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price Weighted average exercise price, Granted Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price Weighted average exercise price, Forfeited Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price Weighted average exercise price, balance Weighted average exercise price, Exercisable as of March 31, 2021 Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price Weighted average exercise price, Vested and expected to vest as of March 31, 2021 Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Exercise Price Weighted average remaining contractual term, outstanding Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2 Weighted average remaining contractual term, Exercisable as of March 31, 2021 Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1 Weighted average remaining contractual term, Vested and expected to vest as of March 31, 2021 Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Remaining Contractual Term1 Aggregate intrinsic value, outstanding Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value Aggregate intrinsic value, exercisable as of March 31, 2021 Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1 Aggregate intrinsic value, Vested and expected to vest as of March 31, 2021 Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Aggregate Intrinsic Value Options to purchase shares of common stock granted Vesting period of stock option Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Period1 Stock option vesting percentage Sharebased Compensation Arrangement By Sharebased Payment Award Award Vesting Rights Percentage Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Income Statement Location Income Statement Location [Axis] Income Statement Location Income Statement Location [Domain] Research and Development [Member] Research And Development Expense [Member] General and Administrative [Member] General And Administrative Expense [Member] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Total stock-based compensation expense Allocated Share Based Compensation Expense Unrecognized compensation expense Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Unrecognized compensation expense recognized period Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1 Amount of payment due upon reaching milestone. The minimum annual royalty payment that is required under a contractual arrangement. Other Commitments [Table] Other Commitments [Table] Legal Entity of Counterparty, Type Accounts Notes Loans And Financing Receivables By Legal Entity Of Counterparty Type [Axis] Legal Entity Type of Counterparty Legal Entity Type Of Counterparty [Domain] Wake Forest University Health Sciences (WFUHS) [Member] WFUHS [Member] Wake Forest University Health Sciences [Member] Indiana University Research and Technology Corporation. IU [Member] Indiana University Research And Technology Corporation [Member] Geographical Statement Geographical [Axis] Geographical Segment Geographical [Domain] Pennsylvania [Member] PENNSYLVANIA Lease Contractual Term Lease Contractual Term [Axis] Lease Contractual Term Lease Contractual Term [Domain] Office. Office [Member] Office [Member] Massachusetts [Member] MOROCCO Real Estate, Type of Property Mortgage Loans On Real Estate Description Type Of Property [Axis] Real Estate Mortgage Loans On Real Estate Name Property Type [Domain] Office Sublease Office Sublease [Member] Office Sublease [Member] First sublease year member. First Sublease Year [Member] First Sublease Year [Member] Final sublease year Final Sublease Year [Member] Final Sublease Year [Member] Sixth sublease year member Sixth Sublease Year Sixth Sublease Year [Member] Office and Lab. Office and Lab [Member] Office And Lab [Member] Other Commitments [Line Items] Other Commitments [Line Items] Milestone payments Milestone Payment Amount Annual royalty pay obligation Minimum Annual Royalty Obligation The amount that may be deducted from consideration due to Licensor 2 as a percentage of consideration paid to Licensor 1, whereby Licensor 1 is the identified party. License agreement consideration deduction percentage License Agreement Consideration Deduction Percentage Amount of payment due for milestones that have been achieved The amount of expense recognized during the period related to milestones. Such amount may include, but is not limited to, amounts due for attainment of milestones as well as deductions granted as part of a license agreement. Milestone expenses Milestone Expenses Milestone payments due Milestone Liability Lease term commencement date. Operating lease term Lessee Operating Lease Term Of Contract Lease extension period Lessee Operating Lease Renewal Term Operating lease liability Operating Lease Liability Lease term commencement date Lease Term Commencement Date Area of office space. Letter of credit Line Of Credit Area of office space Area Of Office Space Lease term expiration date Lease Expiration Date1 Lease security deposits letters of credit Annual base rent Operating Leases Future Minimum Payments Due Future Minimum Sublease Rentals Lease security deposits letters of credit Lease Security Deposit Letters Of Credit Weighted average remaining lease term in years Operating Lease Weighted Average Remaining Lease Term1 Weighted average discount rate Operating Lease Weighted Average Discount Rate Percent Lease expenses Operating Lease Expense Leases [Abstract] Nine months ending December 31, 2021 Lessee Operating Lease Liability Payments Remainder Of Fiscal Year Year ended December 31, 2022 Lessee Operating Lease Liability Payments Due Next Twelve Months Year ended December 31, 2023 Lessee Operating Lease Liability Payments Due Year Two Year ended December 31, 2024 Lessee Operating Lease Liability Payments Due Year Three Year ended December 31, 2025 Lessee Operating Lease Liability Payments Due Year Four Thereafter Lessee Operating Lease Liability Payments Due After Year Four Total lease payments Lessee Operating Lease Liability Payments Due Less: imputed interest Lessee Operating Lease Liability Undiscounted Excess Amount Present value of lease liabilities Period of agreement. Represents extended term of agreement. Agreement Expiration Date. The annual amount of compensation to be paid over the term of a consulting agreement. The number of restricted common units granted. Schedule Of Related Party Transactions By Related Party [Table] Schedule Of Related Party Transactions By Related Party [Table] Research and Development Arrangement, Contract to Perform for Others, Type Research And Development Arrangement Contract To Perform For Others By Type [Axis] Research and Development Arrangement, Contract to Perform for Others, Type Research And Development Arrangement Contract To Perform For Others Type [Domain] Consulting Agreement. Consulting Agreement [Member] Consulting Agreement [Member] New Consulting Agreement Member New Consulting Agreement [Member] New Consulting Agreement [Member] Holdings member. Holdings [Member] Holdings [Member] Future Services. Future Services [Member] Future Services [Member] Remaining Restricted Common Units. Remaining Restricted Common Units [Member] Remaining Restricted Common Units [Member] Vests over forty eight months. Vests Over Forty Eight Months [Member] Vests Over Forty Eight Months [Member] Series a preferred unit purchase agreement. Series A Preferred Unit Purchase Agreement [Member] Series A Preferred Unit Purchase Agreement [Member] Series b bridge unit purchase agreement. Series B Bridge Unit Purchase Agreement [Member] Series B Bridge Unit Purchase Agreement [Member] Second series b bridge unit purchase agreement. Second Series B Bridge Unit Purchase Agreement [Member] Second Series B Bridge Unit Purchase Agreement [Member] Series A and Series B member Series A and Series B [Member] Series A And Series B [Member] Related Party Transaction [Line Items] Related Party Transaction [Line Items] Amount to be paid for consulting services Amount To Be Paid For Consulting Services Research and development expense Restricted common units granted Partners Capital Account Restricted Common Units Granted Award vesting Period of agreement Period Of Agreement Extented period of agreement Extended Period Of Agreement Agreement expiration date Agreement Expiration Date Gross proceeds from sale of equity Proceeds From Issuance Or Sale Of Equity