Entity Central Index Key
Cover [Abstract]
Document Type
Document Type
Amendment Flag
Amendment Flag
Document Period End Date
Document Period End Date
Document Fiscal Year Focus
Document Fiscal Year Focus
Document Fiscal Period Focus
Document Fiscal Period Focus
Entity Registrant Name
Entity Registrant Name
Entity Central Index Key
Current Fiscal Year End Date
Current Fiscal Year End Date
Entity Well-known Seasoned Issuer
Entity Well Known Seasoned Issuer
Entity Current Reporting Status
Entity Current Reporting Status
Entity Interactive Data Current
Entity Interactive Data Current
Entity Voluntary Filers
Entity Voluntary Filers
Entity Filer Category
Entity Filer Category
Entity Small Business
Entity Small Business
Entity Emerging Growth Company
Entity Emerging Growth Company
Entity Shell Company
Entity Shell Company
Entity Common Stock, Shares Outstanding
Entity Common Stock Shares Outstanding
Entity Public Float
Entity Public Float
Entity File Number
Entity File Number
Entity Incorporation, State or Country Code
Entity Incorporation State Country Code
Entity Tax Identification Number
Entity Tax Identification Number
Entity Address, Address Line One
Entity Address Address Line1
Entity Address, Address Line Two
Entity Address Address Line2
Entity Address, City or Town
Entity Address City Or Town
Entity Address, State or Province
Entity Address State Or Province
Entity Address, Postal Zip Code
Entity Address Postal Zip Code
City Area Code
City Area Code
Local Phone Number
Local Phone Number
Document Annual Report
Document Annual Report
Document Transition Report
Document Transition Report
Title of 12(b) Security
Security12b Title
Trading Symbol
Trading Symbol
Security Exchange Name
Security Exchange Name
The amount expected to be received within one year or the normal operating cycle, if longer, as part of a refundable tax incentive program for research and development activities.
Statement Of Financial Position [Abstract]
Assets
Assets [Abstract]
Current assets:
Assets Current [Abstract]
Cash and cash equivalents
Cash And Cash Equivalents At Carrying Value
Marketable securities
Available For Sale Securities Debt Securities Current
Tax incentive receivable
Tax Incentive Receivable Current
Prepaid expenses and other current assets
Prepaid Expense And Other Assets Current
Total current assets
Assets Current
Property and equipment, net
Property Plant And Equipment Net
Operating lease right-of-use assets
Operating Lease Right Of Use Asset
Restricted cash
Restricted Cash Noncurrent
Other assets
Other Assets Noncurrent
Total assets
Assets
Liabilities and Stockholders' Equity
Liabilities And Stockholders Equity [Abstract]
Current liabilities:
Liabilities Current [Abstract]
Accounts payable
Accounts Payable Current
Accrued expenses
Accrued Liabilities Current
Accrued restructuring costs
Restructuring Reserve Current
Operating lease liabilities, current
Operating Lease Liability Current
Notes payable, current
Notes Payable Current
Total current liabilities
Liabilities Current
Notes payable, long-term
Long Term Notes Payable
Operating lease liabilities
Operating Lease Liability Noncurrent
Total liabilities
Liabilities
Commitments and contingencies (Note 10)
Commitments And Contingencies
Stockholders' equity:
Stockholders Equity [Abstract]
Preferred stock; $0.001 par value per share; 5,000,000 shares authorized as of December 31, 2019 and 2018; no shares issued and outstanding as of and December 31, 2019 and 2018
Preferred Stock Value
Common stock, $0.001 par value per share; 115,000,000 shares authorized as of December 31, 2019 and 2018; 37,446,498 and 37,287,221 shares issued and outstanding as of December 31, 2019 and 2018, respectively
Common Stock Value
Additional paid-in capital
Additional Paid In Capital Common Stock
Accumulated deficit
Retained Earnings Accumulated Deficit
Accumulated other comprehensive income (loss)
Accumulated Other Comprehensive Income Loss Net Of Tax
Total stockholders' equity
Stockholders Equity
Total liabilities and stockholders' equity
Liabilities And Stockholders Equity
Preferred stock, par value per share
Preferred Stock Par Or Stated Value Per Share
Preferred stock, shares authorized
Preferred Stock Shares Authorized
Preferred stock, shares issued
Preferred Stock Shares Issued
Preferred stock, shares outstanding
Preferred Stock Shares Outstanding
Common stock, par value per share
Common Stock Par Or Stated Value Per Share
Common stock, shares authorized
Common Stock Shares Authorized
Common stock, shares issued
Common Stock Shares Issued
Common stock, shares outstanding
Common Stock Shares Outstanding
Income Statement [Abstract]
Revenue
Revenues
Operating expenses:
Operating Expenses [Abstract]
Research and development
Research And Development Expense
General and administrative
General And Administrative Expense
Restructuring charges
Restructuring Charges
Total operating expenses
Operating Expenses
Loss from operations
Operating Income Loss
Other income (expense):
Other Income And Expenses [Abstract]
Interest income
Investment Income Interest
Interest expense
Interest Expense
Foreign currency transaction gains (losses), net
Foreign Currency Transaction Gain Loss Before Tax
Total other income (expense), net
Nonoperating Income Expense
Net loss
Net Income Loss
Net loss per share, basic and diluted
Earnings Per Share Basic And Diluted
Weighted average common shares outstanding, basic and diluted
Weighted Average Number Of Share Outstanding Basic And Diluted
Comprehensive loss:
Comprehensive Income Net Of Tax [Abstract]
Net loss
Other comprehensive income:
Other Comprehensive Income Loss Net Of Tax Portion Attributable To Parent [Abstract]
Unrealized gain on marketable securities
Other Comprehensive Income Availableforsale Securities Adjustment Net Of Tax Portion Attributable To Parent
Total other comprehensive income
Other Comprehensive Income Loss Net Of Tax Portion Attributable To Parent
Total comprehensive loss
Comprehensive Income Net Of Tax
The number of shares issued during the period upon exercise of stock options and stock purchase plans.
The value of stock issued during the period upon exercise of stock options and stock purchase plans.
Statement Of Stockholders Equity [Abstract]
Statement [Table]
Statement [Table]
Equity Components
Statement Equity Components [Axis]
Equity Component
Equity Component [Domain]
Common Stock [Member]
Common Stock [Member]
Additional Paid-in Capital [Member]
Additional Paid In Capital [Member]
Accumulated Deficit [Member]
Retained Earnings [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Accumulated Other Comprehensive Income [Member]
Statement [Line Items]
Statement [Line Items]
Beginning balance
Beginning balance, shares
Shares Outstanding
Issuance of common stock, net of issuance costs
Stock Issued During Period Value New Issues
Issuance of common stock, net of issuance costs, shares
Stock Issued During Period Shares New Issues
Issuance of common stock upon exercise of stock options and employee stock purchase plan
Stock Issued During Period Value Stock Options Exercised And Employee Stock Purchase Plan
Issuance of common stock upon exercise of stock options and employee stock purchase plan, shares
Stock Issued During Period Shares Stock Options Exercised And Employee Stock Purchase Plans
Issuance of restricted stock units
Stock Issued During Period Value Restricted Stock Award Net Of Forfeitures
Issuance of restricted stock units, shares
Stock Issued During Period Shares Restricted Stock Award Net Of Forfeitures
Stock-based compensation expense
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
Ending balance
Ending balance, shares
The cash outflow associated with the premium paid on marketable securities.
The increase (decrease) during the reporting period in tax incentive receivable, which represents the amount due from tax authorities.
Public offering costs included in accounts payable.
Statement Of Cash Flows [Abstract]
Cash flows from operating activities:
Net Cash Provided By Used In Operating Activities [Abstract]
Net loss
Profit Loss
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract]
Stock-based compensation expense
Share Based Compensation
Non-cash interest expense
Paid In Kind Interest
Depreciation expense
Depreciation
Impairment of assets
Asset Impairment Charges
Loss on disposal of fixed assets
Gain Loss On Disposition Of Assets
Unrealized foreign currency transaction losses (gains)
Foreign Currency Transaction Gain Loss Unrealized
Premium on marketable securities, net
Premium On Marketable Securities
Amortization of (discount) premium on marketable securities
Investment Income Net Amortization Of Discount And Premium
Changes in operating assets and liabilities:
Increase Decrease In Operating Capital [Abstract]
Prepaid expenses and other current assets
Increase Decrease In Prepaid Deferred Expense And Other Assets
Tax incentive receivable
Increase Decrease In Tax Incentives Receivable
Accounts payable
Increase Decrease In Accounts Payable
Accrued restructuring costs
Increase Decrease In Restructuring Reserve
Accrued expenses and other
Increase Decrease In Accrued Liabilities And Other Operating Liabilities
Other assets
Increase Decrease In Other Noncurrent Assets
Net cash used in operating activities
Net Cash Provided By Used In Operating Activities
Cash flows from investing activities:
Net Cash Provided By Used In Investing Activities [Abstract]
Proceeds from sales and maturities of marketable securities
Proceeds From Sale And Maturity Of Available For Sale Securities
Purchases of marketable securities
Payments To Acquire Available For Sale Securities Debt
Purchases of property and equipment
Payments To Acquire Property Plant And Equipment
Proceeds from sales of property and equipment
Proceeds From Sale Of Property Plant And Equipment
Payments for leasehold improvements on right-of-use assets
Operating Lease Payments Use
Net cash provided by (used in) investing activities
Net Cash Provided By Used In Investing Activities
Cash flows from financing activities:
Net Cash Provided By Used In Financing Activities [Abstract]
Proceeds from issuance of notes payable
Proceeds From Notes Payable
Repayments of notes payable
Repayments Of Notes Payable
Proceeds from exercise of common stock options and employee stock purchase plan
Proceeds From Issuance Of Shares Under Incentive And Share Based Compensation Plans Including Stock Options
Proceeds from public offerings, net of commissions and underwriting discounts
Proceeds From Issuance Of Common Stock
Payments of public offering costs
Payments Of Stock Issuance Costs
Net cash (used in) provided by financing activities
Net Cash Provided By Used In Financing Activities
Net (decrease) increase in cash, cash equivalents and restricted cash
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
Cash, cash equivalents and restricted cash at beginning of period
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
Cash, cash equivalents and restricted cash at end of period
Supplemental disclosure of non-cash investing and financing activities:
Cash Flow Noncash Investing And Financing Activities Disclosure [Abstract]
Public offering costs included in accounts payable
Public Offering Cost Included In Accounts Payable
Right-of-use asset obtained in exchange for operating lease obligation
Right Of Use Asset Obtained In Exchange For Operating Lease Liability
Supplemental disclosure of cash flow information:
Supplemental Cash Flow Information [Abstract]
Cash paid for interest
Interest Paid Net
Documents Incorporated by Reference
Documents Incorporated By Reference [Text Block]
Accounting Policies [Abstract]
Nature of the Business and Basis of Presentation
Business Description And Basis Of Presentation [Text Block]
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Fair Value Disclosures [Abstract]
Fair Value Measurements and Marketable Securities
Fair Value Disclosures [Text Block]
Property Plant And Equipment [Abstract]
Property and Equipment, net
Property Plant And Equipment Disclosure [Text Block]
Payables And Accruals [Abstract]
Accrued Expenses
Accounts Payable Accrued Liabilities And Other Liabilities Disclosure Current [Text Block]
Debt Disclosure [Abstract]
Notes Payable
Debt Disclosure [Text Block]
Equity [Abstract]
Stockholders' Equity
Stockholders Equity Note Disclosure [Text Block]
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
Stock-Based Awards
Disclosure Of Compensation Related Costs Share Based Payments [Text Block]
Earnings Per Share [Abstract]
Net Loss Per Share
Earnings Per Share [Text Block]
Commitments And Contingencies Disclosure [Abstract]
Commitments and Contingencies
Commitments And Contingencies Disclosure [Text Block]
Income Tax Disclosure [Abstract]
Income Taxes
Income Tax Disclosure [Text Block]
Compensation And Retirement Disclosure [Abstract]
Retirement Plan
Pension And Other Postretirement Benefits Disclosure [Text Block]
Research And Development [Abstract]
Australia Research and Development Tax Incentive
Research Development And Computer Software Disclosure [Text Block]
Restructuring And Related Activities [Abstract]
Restructuring
Restructuring And Related Activities Disclosure [Text Block]
Quarterly Financial Information Disclosure [Abstract]
Quarterly Financial Data (Unaudited)
Quarterly Financial Information [Text Block]
Use of Estimates
Use Of Estimates
Cash Equivalents
Cash And Cash Equivalents Policy [Text Block]
Concentration of Credit Risk and of Significant Suppliers
Concentration Risk Credit Risk
Marketable Securities
Marketable Securities Policy
Deferred Offering Costs
Deferred Charges Policy [Text Block]
Property and Equipment
Property Plant And Equipment Policy [Text Block]
Impairment of Long-Lived Assets
Impairment Or Disposal Of Long Lived Assets Policy [Text Block]
Research and Development Costs
Research And Development Expense Policy
Disclosure of accounting policy for costs associated with research and development contracts.
Research Contract Costs and Accruals
Research Contract Costs And Accruals Policy [Text Block]
Patent Costs
Intangible Assets Finite Lived Policy
Accounting for Stock-Based Compensation
Share Based Compensation Option And Incentive Plans Policy
Income Taxes
Income Tax Policy [Text Block]
Segment Data
Segment Reporting Policy Policy [Text Block]
Comprehensive Loss
Comprehensive Income Policy Policy [Text Block]
Net Loss Per Share
Earnings Per Share Policy [Text Block]
Recently Issued and Adopted Accounting Pronouncements
New Accounting Pronouncements Policy Policy [Text Block]
Summary of Cash Equivalents and Marketable Securities
Fair Value Assets Measured On Recurring And Nonrecurring Basis Table [Text Block]
Summary of Marketable Securities
Schedule Of Available For Sale Securities Reconciliation Table [Text Block]
Schedule of Property Plant and Equipment Net
Property Plant And Equipment [Text Block]
Schedule of Accrued Expenses
Schedule Of Accrued Liabilities Table [Text Block]
Tabular disclosure of notes payable. Includes, but is not limited to, current and long-term portions.
Schedule of Notes Payable
Schedule Of Notes Payable Table [Text Block]
Schedule of Estimated Future Principal Payments
Schedule Of Maturities Of Long Term Debt Table [Text Block]
Award Type
Award Type [Axis]
Award Type
Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain]
Time based options.
Options with Time-Based Vesting Conditions [Member]
Time Based Stock Options [Member]
Market based stock options.
Options with Market-Based Vesting Conditions [Member]
Market Based Stock Options [Member]
Assumptions used to Determine Fair Value of Stock Options Granted
Schedule Of Share Based Payment Award Stock Options Valuation Assumptions Table [Text Block]
Summary of Stock Option Activity
Schedule Of Share Based Compensation Stock Options Activity Table [Text Block]
Summary of Restricted Stock Units Activity
Schedule Of Share Based Compensation Restricted Stock Units Award Activity Table [Text Block]
Summary of Stock-Based Compensation Expense Related to Stock Options and Restricted Common Stock
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Text Block]
Computation of Basic and Diluted Earnings Per Share
Schedule Of Earnings Per Share Basic And Diluted Table [Text Block]
Summary of Common Stock Equivalents Outstanding
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block]
Schedule of Future Minimum Lease Payments for Operating Leases
Lessee Operating Lease Liability Maturity Table [Text Block]
Schedule of Components of Leases Expense
Lease Cost Table [Text Block]
Schedule of weighted average remaining lease term and weighted average discount rate of operating leases.
Schedule of Weighted Average Remaining Lease Term and Weighted Average Discount Rate of Operating Leases
Schedule Of Weighted Average Remaining Lease Term And Weighted Average Discount Rate Of Operating Leases Table [Text Block]
Schedule of supplemental cash flow information related to leases.
Schedule of Supplemental Cash Flow Information Related to Leases
Schedule Of Supplemental Cash Flow Information Related To Leases Table [Text Block]
Schedule of Domestic and Foreign Components of Loss Before Income Taxes
Schedule Of Income Before Income Tax Domestic And Foreign Table [Text Block]
Reconciliation of Federal Statutory Income Tax Rate
Schedule Of Effective Income Tax Rate Reconciliation Table [Text Block]
Schedule of Net Deferred Tax Assets
Schedule Of Deferred Tax Assets And Liabilities Table [Text Block]
Summary Changes in the Valuation Allowance for Deferred Tax Assets
Summary Of Valuation Allowance [Text Block]
Summary of Accrued Restructuring Costs
Schedule Of Restructuring Reserve By Type Of Cost [Text Block]
Summary of Restructuring Charges by Category
Schedule Of Restructuring And Related Costs [Text Block]
Schedule of Unaudited Consolidated Financial Statements
Schedule Of Quarterly Financial Information Table [Text Block]
Organization Consolidation And Presentation Of Financial Statements [Abstract]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Table]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Table]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Table]
Business Acquisition
Business Acquisition [Axis]
Business Acquisition, Acquiree
Business Acquisition Acquiree [Domain]
Chondrial therapeutics inc.
Chondrial Therapeutics Inc. [Member]
Chondrial Therapeutics Inc [Member]
Collaborative Arrangement and Arrangement Other than Collaborative
Type Of Arrangement [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Arrangements And Nonarrangement Transactions [Member]
Company stockholders prior to merger.
Company Stockholders Prior to Merger [Member]
Company Stockholders Prior To Merger [Member]
Equity Interest Type
Equity Interest Issued Or Issuable By Type [Axis]
Equity Interest Issued or Issuable, Type
Equity Interest Issued Or Issuable Type [Domain]
Chondrial security holders.
Chondrial Security Holders [Member]
Chondrial Security Holders [Member]
Statistical Measurement
Range [Axis]
Statistical Measurement
Range [Member]
Maximum [Member]
Maximum [Member]
Minimum [Member]
Minimum [Member]
Sale of Stock
Subsidiary Sale Of Stock [Axis]
Sale of Stock
Sale Of Stock Name Of Transaction [Domain]
Follow-on offerings.
Public Offering [Member]
Follow On Offerings [Member]
Long-term Debt, Type
Longterm Debt Type [Axis]
Long-term Debt, Type
Longterm Debt Type [Domain]
Term Loan [Member]
Term Loan [Member]
Term Loan [Member]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]
Entity incorporation date
Entity Incorporation Date Of Incorporation
The number of positions eliminated during the period as a percentage of total positions eliminated during the period in connection with the restructuring plan(s) and subsequent attrition.
Restructuring and other attrition, percentage of workforce reduction
Restructuring And Other Attrition Number Of Positions Eliminated Period Percent
Date of merger agreement.
The percentage of outstanding shares of the company's common stock on a fully diluted basis that are expected to be owned immediately following the merger.
Date of merger agreement
Date Of Merger Agreement
Percentage of expected diluted common shares immediately after merger
Percentage Of Outstanding Shares Of Common Stock Owned After Merger
Merger agreement termination fee to be paid by either party to other party upon termination of agreement.
The amount of third party expenses that may be required to be paid to the other party in the event of termination of the merger agreement.
Merger agreement termination fee to be paid by either party to other party upon termination of agreement
Merger Agreement Termination Fee To Be Paid By Either Party To Other Party Upon Termination Of Agreement
Additional third party expenses to be paid by either party to other party upon termination of merger agreement
Third Party Expenses Required To Pay To Other Party
The minimum amount of net cash required to be held as a condition of the merger agreement.
Merger agreement minimum required net cash thresholds
Merger Agreement Minimum Required Net Cash Thresholds
Beneficiary interest percentage in outstanding common stock
Variable Interest Entity Ownership Percentage
The minimum default amount over which the lender may exercise remedies against the Company.
Net proceeds from sale of securities.
Net proceeds from sale of securities
Net Proceeds From Sale Of Securities
Issuance of common stock
Share price per share
Shares Issued Price Per Share
Net proceeds from public offering, after underwriting discount, commission and offering expenses
Aggregate principal balance
Debt Instrument Face Amount
Loan agreement minimum liquidity required
Restricted Cash And Investments
Credit facility default amount
Line Of Credit Facility Debt Default Minimum Amount
Total cash, cash equivalents and marketable securities
Cash Cash Equivalents And Short Term Investments
Summary of significant accounting policies.
Summary of significant accounting policies.
Summary Of Significant Accounting Policies [Table]
Summary Of Significant Accounting Policies [Table]
Property, Plant and Equipment, Type
Property Plant And Equipment By Type [Axis]
Property, Plant and Equipment, Type
Property Plant And Equipment Type [Domain]
Equipment, furniture and fixtures and office equipment.
Equipment, Furniture and Fixtures and Office Equipment [Member]
Equipment Furniture And Fixtures And Office Equipment [Member]
Adjustments for New Accounting Pronouncements
Adjustments For New Accounting Pronouncements [Axis]
Type of Adoption
Type Of Adoption [Member]
ASU 2016-02 [Member]
Accounting Standards Update201602 [Member]
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Estimated useful life
Property Plant And Equipment Useful Life
Impairment losses on long-lived assets
Impairment Of Long Lived Assets Held For Use
The minimum likelihood percentage threshold used to determine the amount of tax benefit to be recognized.
Percentage of likelihood to be realized upon ultimate settlement, description
Likelihood Percentage Minimum
Operating lease asset
Operating lease liability
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value Hierarchy and NAV
Fair Value By Fair Value Hierarchy Level [Axis]
Fair Value Hierarchy and NAV
Fair Value Measurements Fair Value Hierarchy [Domain]
Quoted Prices in Active Markets, (Level 1) [Member]
Fair Value Inputs Level1 [Member]
Significant Other Observable Inputs (Level 2) [Member]
Fair Value Inputs Level2 [Member]
Significant Unobservable Inputs (Level 3) [Member]
Fair Value Inputs Level3 [Member]
Investment Type
Investment Type [Axis]
Investments
Investment Type Categorization [Member]
Money Market Funds [Member]
Money Market Funds [Member]
U.S. Government Securities [Member]
U S Government Corporations And Agencies Securities [Member]
Commercial Paper [Member]
Commercial Paper [Member]
Corporate Bonds [Member]
Corporate Bond Securities [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Cash equivalents
Cash And Cash Equivalents Fair Value Disclosure
Total cash equivalents and marketable securities
Assets Fair Value Disclosure
Debt Securities Available For Sale [Table]
Debt Securities Available For Sale [Table]
U.S. Government Securities (Due within 1 Year) [Member]
Corporate Bonds (Due within 1 Year) [Member]
Commercial Paper (Due within 1 Year) [Member]
Schedule of Available-for-sale Securities [Line Items]
Schedule Of Available For Sale Securities [Line Items]
Amortized Cost
Available For Sale Debt Securities Amortized Cost Basis
Gross Unrealized Gains
Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
Gross Unrealized Losses
Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
Fair Value
Property Plant And Equipment Capitalized Interest Costs [Abstract]
Property Plant And Equipment Capitalized Interest Costs [Abstract]
Schedule Of Property Plant And Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Office Equipment [Member]
Office Equipment [Member]
Furniture and Fixtures [Member]
Furniture And Fixtures [Member]
Equipment [Member]
Equipment [Member]
Leasehold Improvements [Member]
Leasehold Improvements [Member]
Property, Plant and Equipment [Line Items]
Property Plant And Equipment [Line Items]
Property and equipment, Useful Life
Property and equipment, gross
Property Plant And Equipment Gross
Less: Accumulated depreciation
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
Property and equipment, net
Carrying value as of the balance sheet date of obligations incurred through that date and payable for expenses related to research and development. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).
Accrued payroll and related expenses
Employee Related Liabilities Current
Accrued research and development expenses
Accrued Research And Development Expense Current
Accrued professional fees
Accrued Professional Fees Current
Accrued other
Other Accrued Liabilities Current
Total accrued expenses and other
Accrued Liabilities And Other Liabilities
Debt Instrument [Table]
Debt Instrument [Table]
Variable Rate
Variable Rate [Axis]
Variable Rate
Variable Rate [Domain]
Prime Rate [Member]
Prime Rate [Member]
Secured Debt [Member]
Secured Debt [Member]
Credit Facility
Credit Facility [Axis]
Credit Facility
Credit Facility [Domain]
Two thousand and fourteen credit facility.
2014 Credit Facility [Member]
Two Thousand And Fourteen Credit Facility [Member]
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Maximum borrowings under term loan
The fee, as a percentage of the term loan, due as a final payment.
Debt facility description
Debt Instrument Description
Debt maturity date
Debt Instrument Maturity Date
Debt facility interest rate description
Debt Instrument Description Of Variable Rate Basis
Debt facility variable annual interest rate above prime rate
Debt Instrument Basis Spread On Variable Rate1
Debt facility prime annual interest rate
Debt Instrument Interest Rate During Period
Debt facility fee percentage
Debt Instrument Fee Percentage
Charges to interest expense of debt outstanding
Debt Instrument Increase Accrued Interest
Debt facility effective annual interest rate
Debt Instrument Interest Rate Effective Percentage
The amount of cash, cash equivalents and marketable securities the Company is required to maintain, as a percentage of the total outstanding principal balance of a loan.
Percentage equivalent of cash, cash equivalents and marketable securities balance
Restricted Cash And Investments As Percentage Of Outstanding Principal Amount
The percentage of its cash, cash equivalents, and marketable securities that the Company is obligated to maintain a balance of.
The percentage of the principal balance that the Company must immediately secure if it does not meet its balance obligations of cash, cash equivalents and marketable securities.
Debt facility covenant description
Debt Instrument Covenant Description
Unrestricted cash, cash equivalents and marketable securities
Percentage of cash, cash equivalents and marketable securities
Cash Cash Equivalents And Short Term Investments Percentage
Percentage of principal balance to be secured in restricted cash account for not to be considered an event of default
Percentage Of Principal Balance To Be Secured In Restricted Cash Account
The aggregate amount of cash permitted to be maintained by the Australian subsidiary.
Aggregate value of cash maintained by Australian subsidiary, limit
Debt Instrument Restrictive Covenants Investment In Subsidiaries
Carrying value as of the balance sheet date of notes payable before accretion (with maturities initially due after one year or beyond the operating cycle if longer), excluding current portion.
Debt Instruments [Abstract]
Notes payable
Notes Payable
Less: current portion
Notes payable, net of current portion
Long Term Notes Payable Before Accretion
Accretion related to final payment
Debt Instrument Periodic Payment Terms Balloon Payment To Be Paid
Notes payable, long term
2020
Long Term Debt Maturities Repayments Of Principal In Next Twelve Months
2021
Long Term Debt Maturities Repayments Of Principal In Year Two
Long-term Debt
Long Term Debt
Interest expense on term loan
Debt Instrument Periodic Payment Interest
Interest expense on credit facility
Line Of Credit Facility Periodic Payment Interest
Public offering.
Public Offering [Member]
Public Offering [Member]
Related Party
Related Party Transactions By Related Party [Axis]
Related Party
Related Party [Domain]
Cowen and company limited liability company.
Cowen [Member]
Cowen And Company Limited Liability Company [Member]
At-the-market equity offering program.
ATM Offering Program [Member]
At The Market Equity Offering Program [Member]
Share price per share
Proceeds from offering, net of commissions and underwriting discounts
The potential aggregate gross sales proceeds available under a sales agreement to sell shares of the Company's common stock.
The fee for services as a percentage of gross proceeds resulting from the sale of shares of common stock under a sales agreement.
Description of sales agreement..
Aggregate gross sales proceeds under sales agreement
Aggregate Gross Sales Proceeds Under Sales Agreement
Percentage of compensation for services equal to gross proceeds
Percentage Of Compensation For Services Equal To Gross Proceeds
Sales agreement, description
Sales Agreement Description
Preferred stock, par value
Common stock, par value
Compensation Related Costs [Abstract]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Plan Name
Plan Name [Axis]
Plan Name
Plan Name [Domain]
Two thousand fourteen stock option and incentive plan.
2014 Stock Option and Incentive Plan [Member]
Two Thousand Fourteen Stock Option And Incentive Plan [Member]
Two thousand and fourteen employee stock purchase plan.
2014 Employee Stock Purchase Plan [Member]
Two Thousand And Fourteen Employee Stock Purchase Plan [Member]
Grants outside of two thousand fourteen plan.
Grants Outside of 2014 Plan [Member]
Grants Outside Of Two Thousand Fourteen Plan [Member]
Vesting
Vesting [Axis]
Vesting
Vesting [Domain]
First Anniversary of Grant Date [Member]
Share Based Compensation Award Tranche One [Member]
Title of Individual
Title Of Individual [Axis]
Title of Individual
Title Of Individual With Relationship To Entity [Domain]
Non Employee [Member]
Non Employee [Member]
Nonemployee [Member]
CEO [Member]
Chief Executive Officer [Member]
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units R S U [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Shares of common stock reserved for issuance
Common Stock Capital Shares Reserved For Future Issuance
Percentage of outstanding shares of common stock
Share Based Compensation Arrangement By Share Based Payment Award Percentage Of Outstanding Stock Maximum
Shares available for grant
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant
Shares added to plan
Share Based Compensation Arrangement By Share Based Payment Award Options Other Increases Decreases In Period
Stock based compensation, stock options granted
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
Vesting period of stock option
Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Period1
Term of stock option
Sharebased Compensation Arrangement By Sharebased Payment Award Expiration Period
Stock option vesting percentage
Sharebased Compensation Arrangement By Sharebased Payment Award Award Vesting Rights Percentage
Stock option vesting description
Share Based Compensation Arrangement By Share Based Payment Award Description
Risk-free interest rate
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
Expected term (in years)
Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
Expected volatility
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
Expected dividend yield
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
Shares issuable under options, beginning balance
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
Shares issuable under options, granted
Shares issuable under options, exercised
Stock Issued During Period Shares Stock Options Exercised
Shares issuable under options, forfeited
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
Shares issuable under options, ending balance
Shares issuable under options, options exercisable
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
Weighted average exercise price, beginning balance
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
Weighted average exercise price, granted
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
Weighted average exercise price, exercised
Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
Weighted average exercise price, forfeited
Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
Weighted average exercise price, ending balance
Weighted average exercise price, options exercisable
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
Average remaining contractual life, outstanding
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
Average remaining contractual life, options exercisable
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
Aggregate intrinsic value, outstanding
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
Aggregate intrinsic value, options exercisable
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
Aggregate intrinsic value of stock options exercised
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
Proceeds from exercise of common stock options
Proceeds From Stock Options Exercised
Weighted average grant-date fair value of stock options granted
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
Number of outstanding unvested shares held by nonemployees
Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Number Of Shares
Stock based compensation, stock options forfeited
The number of shares, as a percentage, that will vest upon achievement of the target.
Number of shares that will vest upon achievement of the target, as a percentage
Share Based Compensation Arrangement By Share Based Payment Award Options Grant Target Shares Percentage
The total grant-date fair value of Price Target Options.
Total fair value of Price Target Options
Share Based Compensation Arrangement By Share Based Payment Award Aggregate Grant Date Fair Value
Weighted average fair value of Price Target Options
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested Weighted Average Grant Date Fair Value
Aggregate intrinsic value of Price Target Options
Unvested, beginning balance
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
Granted
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period
Vested
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period
Forfeited
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeited In Period
Unvested, ending balance
Weighted average exercise price per share, beginning balance
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
Weighted average grant date fair value, granted
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Weighted Average Grant Date Fair Value
Weighted average grant date fair value, vested
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Weighted Average Grant Date Fair Value
Weighted average grant date fair value, forfeited
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeitures Weighted Average Grant Date Fair Value
Weighted average exercise price per share, ending balance
Number of restricted stock units granted
Weighted average grant-date fair value of restricted stock units granted
Aggregate intrinsic value of restricted stock units vested during the period
Sharebased Compensation Arrangement By Sharebased Payment Award Equity Instruments Other Than Options Aggregate Intrinsic Value Vested
First offering period start date.
First offering period end date.
Second offering period start date.
Second offering period end date.
Commencement date of first offering period
First Offering Period Start Date
End date of first offering period
First Offering Period End Date
Commencement date of second offering period
Second Offering Period Start Date
End date of second offering period
Second Offering Period End Date
Discount from market price of the company's common stock offering
Sharebased Compensation Arrangement By Sharebased Payment Award Purchase Price Of Common Stock Percent
Stock-based awards, shares
Stock Issued During Period Shares Share Based Compensation
Income Statement Location
Income Statement Location [Axis]
Income Statement Location
Income Statement Location [Domain]
Research and Development [Member]
Research And Development Expense [Member]
General and Administrative [Member]
General And Administrative Expense [Member]
Total stock-based compensation expense
Allocated Share Based Compensation Expense
Unrecognized stock-based compensation cost
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized
Stock-based compensation recognized weighted average period
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1
Numerator [Abstract]
Denominator [Abstract]
Earning Per Share [Abstract]
Earning Per Share [Abstract]
Numerator:
Numerator [Abstract]
Denominator:
Denominator [Abstract]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Antidilutive Securities
Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis]
Antidilutive Securities, Name
Antidilutive Securities Name [Domain]
Options to Purchase Common Stock [Member]
Employee Stock Option [Member]
Restricted Stock Units [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Total potentially dilutive shares
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
Area of office space.
Lease commencement date.
Other Commitments [Table]
Other Commitments [Table]
Entity By Location
Entity By Location [Axis]
Location
Location [Domain]
Boston
Center Plaza, Boston [Member]
Boston [Member]
Geographical
Statement Geographical [Axis]
Geographical
Segment Geographical [Domain]
Massachusetts [Member]
MASSACHUSETTS
Lease Arrangement, Type
Lease Arrangement Type [Axis]
Lease Arrangement, Type
Lease Arrangement Type [Domain]
Shigo Center Plaza Owners LLC.
Shigo Center Plaza Owners LLC [Member]
Shigo Center Plaza Owners L L C [Member]
Additional Office Space [Member]
Additional Boston Office Space [Member]
Additional Office Space [Member]
Office Space Lease [Member]
Boston Office Space [Member]
Office Space Lease [Member]
Additional Office Space two [Member]
San Diego Office Space [Member]
Additional Office Space Two [Member]
Counterparty Name
Counterparty Name [Axis]
Counterparty Name
Repurchase Agreement Counterparty Name [Domain]
Unrelated Third Party Member
Unrelated Third Party [Member]
Unrelated Third Party [Member]
Scenario
Statement Scenario [Axis]
Scenario
Scenario Unspecified [Domain]
Scenario Forecast [Member]
Scenario Forecast [Member]
Category of Item Purchased
Long Term Purchase Commitment By Category Of Item Purchased [Axis]
Long-term Purchase Commitment, Category of Item Purchased
Long Term Purchase Commitment Category Of Item Purchased [Domain]
Pre Commercialization Milestones [Member]
Pre Commercialization Milestones [Member]
Pre Commercialization Milestones [Member]
Product Commercialization Milestones [Member]
Product Commercialization Milestones [Member]
Product Commercialization Milestones [Member]
Subsequent Licensed Product [Member]
Subsequent Licensed Product [Member]
Subsequent Licensed Product [Member]
Other Commitments [Line Items]
Other Commitments [Line Items]
Area of office space
Area Of Office Space
Operating lease term
Lessee Operating Lease Term Of Contract
Lease extension period
Lessee Operating Lease Renewal Term
Letter of credit
Line Of Credit
Operating lease, existence of option to extend
Lessee Operating Lease Existence Of Option To Extend
Total lease payments over the initial term
Lessee Operating Lease Liability Payments Due
Lease commencement date
Lease Commencement Date
The number of options available to extend an operating lease.
Sublease area of real estate property.
Sublease Expiration Date
Lease expiration date
Lease Expiration Date1
Number of options to extend lease
Operating Leases Number Of Options To Extend Lease
Subleased area
Sublease Area Of Real Estate Property
Sublease expiration date
Sublease Expiration Date
Sublease rental income
Sublease Income
Impairment loss on operating lease right-of-use asset
Operating Lease Impairment Loss
Leases [Abstract]
2020
Lessee Operating Lease Liability Payments Due Next Twelve Months
2021
Lessee Operating Lease Liability Payments Due Year Two
2022
Lessee Operating Lease Liability Payments Due Year Three
2023
Lessee Operating Lease Liability Payments Due Year Four
2024
Lessee Operating Lease Liability Payments Due Year Five
Thereafter
Lessee Operating Lease Liability Payments Due After Year Five
Total lease payments
Less: imputed interest
Lessee Operating Lease Liability Undiscounted Excess Amount
Present value of lease liabilities
Operating Lease Liability
Operating leases future minimum payments due in six years.
2019
Operating Leases Future Minimum Payments Due Current
2020
Operating Leases Future Minimum Payments Due In Two Years
2021
Operating Leases Future Minimum Payments Due In Three Years
2022
Operating Leases Future Minimum Payments Due In Four Years
2023
Operating Leases Future Minimum Payments Due In Five Years
2024
Operating Leases Future Minimum Payments Due In Six Years
Thereafter
Operating Leases Future Minimum Payments Due Thereafter
Total lease payments
Operating Leases Future Minimum Payments Due
Lease expense
Lease Cost
Operating lease cost
Operating Lease Cost
Short-term lease cost
Short Term Lease Cost
Sublease income
Total lease cost
Weighted average remaining lease term in years
Operating Lease Weighted Average Remaining Lease Term1
Weighted average discount rate
Operating Lease Weighted Average Discount Rate Percent
Cash paid for amounts included in the measurement of lease liabilities.
Right-of-use assets obtained in exchange for lease obligations.
Cash paid for amounts included in the measurement of lease liabilities:
Cash Paid For Amounts Included In Measurement Of Lease Liabilities [Abstract]
Operating cash flows from operating leases
Operating Lease Payments
Investing cash flows from operating leases
Right-of-use assets obtained in exchange for lease obligations:
Right Of Use Assets Obtained In Exchange For Lease Obligations [Abstract]
Operating leases
Amount of payment due upon reaching milestone.
Maximum fee the Company is obligated to pay per licensed product.
Milestone payments
Milestone Payment Amount
Licensing fees per product maximum
Licensing Fees Per Product Maximum
Amount of payment due for milestones that have been achieved
Milestone payments due
Milestone Liability
Income Taxes Disclosure [Line Items]
Income Taxes Disclosure [Table]
Income Taxes Disclosure [Table]
Income Taxes Disclosure [Table]
Income Tax Authority
Income Tax Authority [Axis]
Income Tax Authority
Income Tax Authority [Domain]
Domestic Tax Authority [Member]
Domestic Country [Member]
State and Local Jurisdiction [Member]
State And Local Jurisdiction [Member]
Tax Period
Tax Period [Axis]
Tax Period
Tax Period [Domain]
No expiration.
No Expiration [Member]
No Expiration [Member]
Earliest Tax Year [Member]
Earliest Tax Year [Member]
Income Taxes Disclosure [Line Items]
Income Taxes Disclosure [Line Items]
Income tax benefit
Income Tax Expense Benefit
Domestic
Income Loss From Continuing Operations Before Income Taxes Domestic
Foreign
Income Loss From Continuing Operations Before Income Taxes Foreign
Loss before income taxes
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
Federal statutory income tax rate
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
Federal and state research and development tax credit
Effective Income Tax Rate Reconciliation Tax Credits Research
State taxes, net of federal benefit
Effective Income Tax Rate Reconciliation State And Local Income Taxes
Stock compensation expense
Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
Nondeductible Australia research and development expenses
Effective Income Tax Rate Reconciliation Nondeductible Expense Research And Development
Impact of federal rate change related to tax reform
Effective Income Tax Rate Reconciliation Change In Enacted Tax Rate
Other items
Effective Income Tax Rate Reconciliation Other Reconciling Items Percent
Change in deferred tax asset valuation allowance
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
Effective income tax rate
Effective Income Tax Rate Continuing Operations
Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from accrued expenses.
Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences not separately disclosed.
Amount before allocation of valuation allowances of deferred tax asset attributable to operating lease liability.
Amount of deferred tax liability attributable to operating lease right of use asset.
Noncurrent deferred tax assets:
Deferred Tax Assets Net Noncurrent Classification [Abstract]
Capitalized research and development expenses
Deferred Tax Assets In Process Research And Development
Net operating loss carryforwards
Deferred Tax Assets Operating Loss Carryforwards
Tax credit carryforwards
Deferred Tax Assets Tax Credit Carryforwards
Capitalized legal expenses
Deferred Tax Assets Tax Deferred Expense Reserves And Accruals Legal Settlements
Stock-based compensation
Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost
Accrued expenses
Deferred Tax Assets Tax Deferred Expense Reserves And Accruals Accrued Liabilities Noncurrent
Other temporary differences
Deferred Tax Assets Other Noncurrent
Operating lease liability
Deferred Tax Assets Operating Lease Liability Noncurrent
Total noncurrent deferred tax assets
Deferred Tax Assets Net Noncurrent
Total gross deferred tax assets
Deferred Tax Assets Gross
Noncurrent deferred tax liability:
Deferred Tax Liabilities [Abstract]
Operating lease right-of-use assets
Deferred Tax Liabilities Operating Lease Right Of Use Assets Noncurrent
Valuation allowance
Deferred Tax Assets Valuation Allowance
Net deferred tax assets
Deferred Tax Assets Net
Amount of decrease in the valuation allowance for a specified deferred tax asset.
Amount of increase in the valuation allowance for a specified deferred tax asset.
Valuation allowance as of beginning of year
Decreases recorded as benefit to income tax provision
Valuation Allowance Deferred Tax Asset Change In Amount Decrease
Increases recorded to income tax provision
Valuation Allowance Deferred Tax Asset Change In Amount Increase
Valuation allowance as of end of year
The first year in which a net operating loss carryforward begins to expire.
The first year in which a tax credit carryforward begins to expire.
The amount of limitation on operating loss carryforwards as a percentage of taxable income in any one tax period.
Net operating loss carryforwards
Operating Loss Carryforwards
Net operating loss carryforwards, beginning of expiration period
Net Operating Loss Carry Forward Expiration Year Begin
Operating loss carryforwards, minimum percentage of taxable income in tax period
Operating Loss Carryforwards Minimum Percentage Of Taxable Income In Tax Period
Operating loss carryforwards, description
Operating Loss Carryforwards Limitations On Use
Tax credit carryforward
Tax Credit Carryforward Amount
Research and development tax credit carry forwards, beginning of expiration period
Tax Credit Carry Forward Expiration Year Start
Uncertain tax position
Liability For Uncertain Tax Positions Current
Amount, after allocation of deferred tax liability but before allocation of valuation allowances, of deferred tax asset attributable to deductible differences and carryforwards.
Net deferred tax assets before the valuation allowance
Deferred Tax Assets Net Of Liabilities Before Valuation Allowance
Unrecognized tax benefits
Unrecognized Tax Benefits
Open tax year
Open Tax Year
Defined Contribution Plan [Table]
Defined Contribution Plan [Table]
Retirement Plan Type
Retirement Plan Type [Axis]
Retirement Plan Type
Retirement Plan Type [Domain]
Retirement 401K plan.
Retirement 401K Plan [Member]
Retirement401 K Plan [Member]
Simple ira plan.
SIMPLE IRA plan [Member]
S I M P L E I R A Plan [Member]
Defined Contribution Plan Disclosure [Line Items]
Defined Contribution Plan Disclosure [Line Items]
Percentage of employer's contribution on employee's base salary
Defined Contribution Plan Employer Matching Contribution Percent
Contribution expense
Defined Contribution Plan Cost Recognized
The percentage to be refunded pertaining to the tax incentive for qualified research and development activities.
The amount of reduction to research and development expense recorded in the income statement.
The percentage of research and development costs to be reduced.
Tax incentive receivable.
Research and Development Tax Incentive [Line Items]
Research and Development Expenses [Table]
Research And Development Expenses [Table]
Research And Development Expenses [Table]
Consolidated Entities
Consolidated Entities [Axis]
Consolidated Entities
Consolidated Entities [Domain]
Zafgen Australia Pty Limited [Member]
Subsidiaries [Member]
Australia [Member]
AUSTRALIA
Research and Development Tax Incentive [Line Items]
Research And Development Tax Incentive [Line Items]
Percentage of refundable tax incentive
Effective Tax Incentive Rate Related To Research And Development
Reduction to research and development expenses
Tax Incentive Research And Development Activities
Percentage of reduction in research and development costs
Percentage Reduction Research And Development Costs
Unrealized foreign currency exchange gains (losses)
Tax incentive receivable
Tax Incentive Receivable
Number of workforce reduction
Restructuring And Related Cost Number Of Positions Eliminated
Restructuring charges and related costs
Restructuring charges paid
Payments For Restructuring
Restructuring Reserve [Abstract]
Schedule Of Restructuring And Related Costs [Table]
Schedule Of Restructuring And Related Costs [Table]
Restructuring Type
Restructuring Cost And Reserve [Axis]
Type of Restructuring
Type Of Restructuring [Domain]
One-Time Employee Termination Benefits [Member]
One Time Termination Benefits [Member]
Contract Termination Costs [Member]
Contract Termination [Member]
Restructuring Cost And Reserve [Line Items]
Restructuring Cost And Reserve [Line Items]
Accrued restructuring costs
Restructuring charges incurred during the period
Restructuring And Related Cost Incurred Cost
Amounts paid during the period
Accrued restructuring costs
Cash and Cash Equivalents
Cash And Cash Equivalents [Axis]
Cash and Cash Equivalents
Restricted Cash And Cash Equivalents Cash And Cash Equivalents [Member]
Cash [Member]
Cash [Member]
Non Cash [Member]
Non-Cash [Member]
Non Cash [Member]
Operating expenses