If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. Checkbox not checked

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).






SCHEDULE 13D






SCHEDULE 13D






SCHEDULE 13D






SCHEDULE 13D






SCHEDULE 13D




Comment for Type of Reporting Person:
Comprised of shares of common stock held by Deerfield Private Design Fund III, L.P., of which Deerfield Mgmt III, L.P. is the general partner.


SCHEDULE 13D




Comment for Type of Reporting Person:
Comprised of shares of common stock held by Deerfield Healthcare Innovations Fund, L.P., of which Deerfield Mgmt HIF, L.P. is the general partner.


SCHEDULE 13D




Comment for Type of Reporting Person:
Comprised of shares of common stock held by Deerfield Private Design Fund IV, L.P., of which Deerfield Mgmt IV, L.P. is the general partner.


SCHEDULE 13D




Comment for Type of Reporting Person:
Comprised of shares of common stock held by Deerfield Partners, L.P., of which Deerfield Mgmt, L.P. is the general partner.


SCHEDULE 13D




Comment for Type of Reporting Person:
Comprised of (i) an aggregate of 30,606,974 shares of common stock held by Deerfield Private Design Fund III, L.P., Deerfield Private Design Fund IV, L.P., Deerfield Healthcare Innovations Fund, L.P. and Deerfield Partners, L.P., of which Deerfield Management Company, L.P. is the investment manager and (ii) an aggregate of 60,500 shares of common stock issuable upon exercise of options (the "Leff Options") held by Jonathan Leff, an employee of Deerfield Management Company, L.P., for the benefit, and subject to the direction, of Deerfield Management Company, L.P. The Leff Options consist options that were granted to Mr. Leff on July 16, 2020, May 12, 2021, May 10, 2022, May 9, 2023 and May 29, 2024, each of which is fully vested.


SCHEDULE 13D




Comment for Type of Reporting Person:
Comprised of (i) an aggregate of 30,606,974 shares of common stock held by Deerfield Private Design Fund III, L.P., Deerfield Private Design Fund IV, L.P., Deerfield Healthcare Innovations Fund, L.P. and Deerfield Partners, L.P., of which Deerfield Management Company, L.P. is the investment manager and (ii) an aggregate of 60,500 shares of common stock issuable upon exercise of options (the "Leff Options") held by Jonathan Leff, an employee of Deerfield Management Company, L.P., for the benefit, and subject to the direction, of Deerfield Management Company, L.P. The Leff Options consist options that were granted to Mr. Leff on July 16, 2020, May 12, 2021, May 10, 2022, May 9, 2023 and May 29, 2024, each of which is fully vested. Mr. Flynn is the sole manager of the general partner of each of Deerfield Mgmt III, L.P., Deerfield Mgmt IV, L.P., Deerfield Mgmt HIF, L.P., Deerfield Mgmt, L.P. and Deerfield Management Company, L.P.


SCHEDULE 13D


 
Deerfield Private Design Fund III, L.P.
 
Signature:/s/ Jonathan Isler
Name/Title:Jonathan Isler, Attorney-in-Fact
Date:07/31/2025
 
Deerfield Healthcare Innovations Fund, L.P.
 
Signature:/s/ Jonathan Isler
Name/Title:Jonathan Isler, Attorney-in-Fact
Date:07/31/2025
 
Deerfield Private Design Fund IV, L.P.
 
Signature:/s/ Jonathan Isler
Name/Title:Jonathan Isler, Attorney-in-Fact
Date:07/31/2025
 
Deerfield Partners, L.P.
 
Signature:/s/ Jonathan Isler
Name/Title:Jonathan Isler, Attorney-in-Fact
Date:07/31/2025
 
Deerfield Mgmt III, L.P.
 
Signature:/s/ Jonathan Isler
Name/Title:Jonathan Isler, Attorney-in-Fact
Date:07/31/2025
 
Deerfield Mgmt HIF, L.P.
 
Signature:/s/ Jonathan Isler
Name/Title:Jonathan Isler, Attorney-in-Fact
Date:07/31/2025
 
Deerfield Mgmt IV, L.P.
 
Signature:/s/ Jonathan Isler
Name/Title:Jonathan Isler, Attorney-in-Fact
Date:07/31/2025
 
Deerfield Mgmt, L.P.
 
Signature:/s/ Jonathan Isler
Name/Title:Jonathan Isler, Attorney-in-Fact
Date:07/31/2025
 
Deerfield Management Company, L.P.
 
Signature:/s/ Jonathan Isler
Name/Title:Jonathan Isler, Attorney-in-Fact
Date:07/31/2025
 
James E. Flynn
 
Signature:/s/ Jonathan Isler
Name/Title:Jonathan Isler, Attorney-in-Fact
Date:07/31/2025

 

Schedule A

 

General Partner of Deerfield Private Design Fund III, L.P.

 

The general partner of Deerfield Private Design Fund III, L.P. is Deerfield Mgmt III, L.P. The address of the principal business and/or principal office of Deerfield Mgmt III, L.P. and Deerfield Private Design Fund III, L.P. is 345 Park Avenue South, 12th Floor, New York, New York 10010.

 

General Partner of Deerfield Mgmt III, L.P.

 

The general partner of Deerfield Mgmt III, L.P. is Deerfield UGP, LLC. The address of the principal business and/or principal office of Deerfield Mgmt III, L.P. and Deerfield UGP, LLC is 345 Park Avenue South, 12th Floor, New York, New York 10010.

 

General Partner of Deerfield Healthcare Innovations Fund, L.P.

 

The general partner of Deerfield Healthcare Innovations Fund, L.P. is Deerfield Mgmt HIF, L.P. The address of the principal business and/or principal office of Deerfield Healthcare Innovations Fund, L.P. and Deerfield Mgmt HIF, L.P. is 345 Park Avenue South, 12th Floor, New York, New York 10010.

 

General Partner of Deerfield Mgmt HIF, L.P.

 

The general partner of Deerfield Mgmt HIF, L.P. is Deerfield UGP, LLC. The address of the principal business and/or principal office of Deerfield Mgmt HIF, L.P. and Deerfield UGP, LLC is 345 Park Avenue South, 12th Floor, New York, New York 10010.

 

General Partner of Deerfield Private Design Fund IV, L.P.

 

The general partner of Deerfield Private Design Fund IV, L.P. is Deerfield Mgmt IV, L.P.. The address of the principal business and/or principal office of Deerfield Mgmt IV, L.P. and Deerfield Private Design Fund IV, L.P. is 345 Park Avenue South, 12th Floor, New York, New York 10010.

 

General Partner of Deerfield Mgmt IV, L.P.

 

The general partner of Deerfield Mgmt IV, L.P. is Deerfield UGP, LLC. The address of the principal business and/or principal office of Deerfield Mgmt IV, L.P. and Deerfield UGP, LLC is 345 Park Avenue South, 12th Floor, New York, New York 10010.

 

General Partner of Deerfield Partners, L.P.

 

The general partner of Deerfield Partners, L.P. is Deerfield Mgmt, L.P. The address of the principal business and/or principal office of Deerfield Mgmt, L.P. and Deerfield Partners, L.P. is 345 Park Avenue South, 12th Floor, New York, New York 10010.

 

General Partner of Deerfield Mgmt III, L.P.

 

The general partner of Deerfield Mgmt III, L.P. is Deerfield UGP, LLC. The address of the principal business and/or principal office of Deerfield Mgmt III, L.P. and Deerfield UGP, LLC is 345 Park Avenue South, 12th Floor, New York, New York 10010.

 

General Partner of Deerfield Management Company, L.P.

 

The general partner of Deerfield Management Company, L.P. is Deerfield UGP LLC. The address of the principal business and/or principal office of Deerfield Management Company, L.P. and Deerfield UGP, LLC is 345 Park Avenue South, 12th Floor, New York, New York 10010.